PeoGlow
New age solution
for the skin unevenness
caused by AGEs and RAGE
The one cause of skin dullness is the uneven skin tone. What makes uneven tone? In our answer, it is the combination of these three color tones on the skin.
AGEs and RAGE: the root causes of unevenness
Recently AGEs are revealed to promote hyperpigmentation and hyperkeratosis via Receptor of AGE (RAGE) like domino effect. It means AGEs and RAGE are the critical causes of not only skin brown tone but also black and gray tone.
Special production
Paeonia albiflora (peony) root extract was found to reduce AGEs and inhibit AGEs-RAGE signal.
Features
Mechanism of PeoGlow
Inhibition of AGEs-RAGE interaction
Breakage of AGEs
These dual function means PeoGlow is enough to stop AGEs-RAGE domino effect!
Effects and benefits
The following test results demonstrate the usefulness of the product.
Activation of proteasome
Measured proteasome activity of human dermal fibroblast cultured with and without 1% JuniperBright.
Reduction of lipofuscin
Measured lipofuscin accumulated area in human dermal fibroblast cultured with and without 1% JuniperBright.
Activation of Autophagy
Measured proteasome activity of human dermal fibroblast cultured with and without 1% JuniperBright.
Improvement of skin L-value
Skin L-Value was measured after using facial emulsion containing 1% JuniperBright for 4 weeks.
Improvement of skin brightness
Internal reflected light was detected after using facial emulsion containing 1% JuniperBright for 4 weeks.
Reduction of pores
3D shape of skin was visualized to calculate pore index after using facial emulsion containing 1% JuniperBright for 4 weeks.
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● INCI Name: Butylene Glycol, Water, Paeonia Albiflora Root Extract
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● Description: A yellowish brown to brown liquid with a characteristic odor
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● Recommended dosage: 1%
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● Toxicity & safety report: Available
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● Japanese Standards of Quasi-drug Ingredients: JSQI APPROVED
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● Chinese INCI: IECIC 2021 Listed
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● Other: HALAL certified
Specifications
Applications
The following applications are recommended.
Facial care: skin blightening care, skin lightening care, anti-aging
Body care: hand, body
FAQ
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Does PeoGlow also prevent glycation?
PeoGlow is a raw material focusing on signals caused by AGEs and RAGE, but it can also be expected to prevent glycation. Depending on the purpose and concept, it may be effective to combine PeoGlow with other products such as Absolage, which is mainly designed to prevent glycation.
Are there any products from other companies that focus on RAGE?
There are a few anti-inflammatory products that focus on the inflammatory aspect of RAGE. On the other hand, PeoGlow is the only product that focuses on the relationship between RAGE and skin unevenness.
How did you evaluate the improvement of skin unevenness?
We used our proprietary unevenness analysis method. In addition to the overall skin color and variation, it is possible to evaluate how easily it is noticeable. We have also confirmed the correlation with the impression people get from the appearance